EN - Anglická CZ - Česká SK - Slovenská PL - Polská RO - Rumunská RU - Ruská TR - Turecká UA - Ukrajinská
EN - Anglická
  • CZ - Česká
  • SK - Slovenská
  • PL - Polská
  • RO - Rumunská
  • RU - Ruská
  • TR - Turecká
  • UA - Ukrajinská

REMOPHAN 75 µg/ml injection solution

Homepage Products Veterinary products REMOPHAN 75 µg/ml injection solution

Hormonal product with luteolytic effect

type of preparative: Hormones
target species animals: Pig, Cattle

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Composition - 1 ml:

Active agent:

Cloprostenolum - D (ut naricum) 0.075 mg

Excipients:

Citric acid, sodium hydroxide, p-chloro-metacresol, water for injection.

Effect method:

Dexcloprostenol - the active lueolytic compound of cloprostenol, the active analogue of F2a prostaglandin causes degeneration of corpus luteum in the luteal phase of estrous cycle creating thus preconditions for an onset of both the heat and the ovulation. The first signs of the commencing heat occur within 48 - 60 hours after the administration of the preparation, while the most suitable time for insemination being about 76 hours after its application.

Pharmacotherapeutical group:

Veterinary luteolytic agent

Indication:

Biotechnical


Cattle:
Heat synchronization and induction in heifers and cows; synchronizing of estrous cycle in donors and recipients included into a program for early embryos transfer.

Sows
Delivery induction

Therapeutic

Functional ovary disorders, postpartum and post-service anestrus; postpuerperal chronic endometritis, pyometra, interruption of both the normal and pathologic pregnancy, combined therapy of follicular cysts.  

Contraindication:

Due to its strong abortive effect, the product shall not be used during the planned and physiologic gravidity, particularly in its second half.

Interaction:

Unknown

Administration:

Intramuscularly

Dosage:

Cattle

2 ml of the preparation should be administered intramuscularly (0.15 mg of the active agent). Heat synchronization: After corpus luteum is found out (6th - 18th day of the cycle) and according to the signs of a heat onset, insemination should be carried out 70 - 120 hours after the application of the preparation. If no heat signs are observed, the application can be repeated on the 11th day after the first application.
Embryo donors:
The preparation should be applied repeatedly on the 3rd day from the beginning of the superovulation preparation (per 2 ml of the preparation should be applied in the morning and in the evening).
Ovary functional disorders:
Insemination should be carried out when the first heat is induced after the preparation was administered. If no signs of heat are observed, the application can be repeated on the 11th day.
Combined therapy of follicular cysts:
The preparation Remophan inj. should be applied on 10th - 14th day after LH-RH was administered, based on the positive ovarian response.
Treatment of postpuerperal uterus diseases:
The preparation Remophan inj. should be repeatedly administered in the interval of 10 days, while insemination shall be performed after the second application only.

Sows

1 ml of the preparation (0.15 mg of the active agent) should be applied in a single dose within the period starting from the 111th day of pregnancy. Most of the deliveries induced in this way occur 19 -  30 hours after the application.

Adverse effects:

Unknown

Warning:

Pregnant women should not handle with the preparation.

Storage:

Store the preparation in an original package at the temperature between 10 °C and 25 °C, in dry place, protected from light. Opened packages shall be consumed within 14 days.

Withdrawal period:

meat: 24 hours
milk: 4 hours

Shelf life:

2 years. Opened packages shall be consumed within 14 days.

Package:

1 x 10 ml in a container


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