EN - Anglická CZ - Česká SK - Slovenská PL - Polská RO - Rumunská RU - Ruská TR - Turecká UA - Ukrajinská
EN - Anglická
  • CZ - Česká
  • SK - Slovenská
  • PL - Polská
  • RO - Rumunská
  • RU - Ruská
  • TR - Turecká
  • UA - Ukrajinská

FIPRON 50 mg spot-on solution for cats

Homepage Products Veterinary products FIPRON 50 mg spot-on solution for cats

Treatment and prevention of flea infestation (Ctenocephalides felis) and related flea allergy dermatitis (FAD) in cats. Treatment and prevention of infestation by ticks and lice in cats.

type of preparative: Antiparasitics
target species animals: Cat

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1 tube (0.5 ml) contains:

Active substance:
  •  Fipronil 50 mg
  • Butylhydroxyanisole (E320)   0.10 mg
  • Butylhydroxytoluene (E321) 0.05 mg

Spot-on solution. Clear, yellow to yellow-green solution.

Target species:



Treatment and prevention of flea infestation (Ctenocephalides felis) and related flea allergy dermatitis (FAD) in cats. Treatment and prevention of infestation by ticks (Ixodes spp.) and lice (Felicola subrostratus) in cats.


In respect of the absence of data do not apply to animals younger than 8 weeks and/or weighing less than 1 kg.
Do not apply to sick animals (systemic disease, fever) and convalescent animals.
Do not use in rabbits. It can cause a serious reaction or death.
Do not use in case of hypersensitivity to the active substances or to any of the excipients.

Special warnings for each target species:

Avoid contact with animal's eyes. With respect to a possible risk of parasite resistance to the active substance, and thus a reduced effect of therapy, the following rules of treatment with ectoparasiticides should be observed:

- Avoid too frequent and recurring use of ectoparasiticides of the same group

- Observe the determined dosage and dosing regimen. Administer the product in doses recommended by the manufacturer so as to ensure the optimal therapeutic effect.

Special precautions for use in animals:

It is important to apply the product on such a place from which the animal cannot lick it and prevent mutual licking of animals after application. Apply the product to the skin surface only. Do not administer orally or parenterally. Avoid administration of the product on the mucous membranes (eyes, nostrils, genitals and injured skin).
In case of fleas, the other animals in the household should be treated with insecticides simultaneously.
Bathing/shampooing of the animal is not recommended within 2 days after application, as well as bathing more frequent than once a week.
Some ticks can attach after treatment, but they are killed 24-48 hours after application. This usually occurs before the tick size changes maximally, which minimizes, but does not exclude the risk of transmission of transmissible diseases.
Fleas from pets often infest animal's crates, places where the animal sleeps and resting areas, such as carpets and soft furnishings which should be treated regularly with suitable insecticides and cleaned with a vacuum cleaner in case of massive infestation and at the beginning of protective measures.

Special precautions to be taken by the person administering the veterinary medicinal product to animals:

People or animals with known hypersensitivity to insecticides or alcohol should avoid contact with the product.
People with epilepsy should handle the product with caution.
The product may cause irritation of eyes and mucous membranes. Therefore, use appropriate protective equipment and avoid contact with eyes, mucous membranes and mouth.
If the product gets into the eye, flush the eye carefully with clean water. In case of serious irritation seek medical attention.
This product may cause skin irritation.
Do not handle treated animals and do not allow children to play with them until the applied product has dried. It is therefore recommended not to treat animals during the day, but early in the evening, and not to allow the recently treated animals to sleep with their owners, especially children.
After application wash your hands with soap and water. Remove contaminated clothing which is in direct contact with the skin.
Take care to avoid finger contact with the content. If this occurs, wash your hands with water and soap.
In case of accidental ingestion seek medical advice immediately and show the package leaflet or label to a practitioner.
Note to physician: After ingestion of a large quantity of the product the following toxicity manifestations can be expected: nausea, vomiting, headache, dizziness, abdominal pain, sweating, restlessness, weakness and tonic-clonic convulsions. The states are transient and usually resolve spontaneously. Excitation of epilepsy can occur in susceptible individuals, or at higher doses. Activated charcoal should be administered in the first step. There is no known specific antidote. Further treatment is symptomatic.
Do not smoke, drink or eat during application.

Adverse reactions  (frequency and seriousness):

Short-term hypersalivation due to the nature of vehicle may occur after licking.
Transient skin reactions at the injection site (hair discolouration and loss, itching, redness) and general pruritus or alopecia were reported very rarely after use. Exceptionally, hypersalivation, reversible neurologic symptoms (hyperaesthesia, depression, nervousness), vomiting difficulty breathing were reported.
Cosmetic defects (bonded hair, white deposits) may occur at the injection site.
Avoid overdose. In case of persisting adverse effects seek the advice of a veterinarian.

Use during pregnancy and lactation:

No studies on the administration of this product to pregnant and lactating bitches are available, therefore use the product only after assessment of the benefit/risk ratio by a veterinarian.

Interaction with other medicinal products and other forms of interaction:

Fipronil and amitraz have a synergic effect.

Amounts to be administered and administration route:

For lack of data the minimum time between two applications is 4 weeks.

Method of administration: spot-on use.

Dosage: Apply 1 tube of 0.5 ml of the skin between the shoulder blades.

Method of administration:

Hold the tube with the neck upwards and knock the neck repeatedly with your finger. Break off the tip carefully by twisting motion. Part the hair of the animal in the withers in front of the shoulder blades until the skin is visible. Place the applicator tip on the skin and press the tube repeatedly to empty the entire contents of the tube directly on the skin.
One dose ensures protection against flea infestation for up to 5 weeks. The product is effective against ticks for 3 to 4 weeks.
In case of indication of allergy dermatitis caused by infestation by fleasCtenocephalides felis, the repeated application of the product is recommended at interval of 4 weeks.

Overdose (symptoms, emergency procedures, antidotes), if necessary:

Do not give the animals more than the recommended dose. The risk of adverse effects (see section Adverse reactions) may increase in case of overdose.

Withdrawal periods:

Not intended for food-producing animals.

Pharmacodynamic properties:

Fipronil is a broad spectrum insecticide/acaricide derived from phenylpyrazole. It is toxic for arthropods after contact with the body surface or if ingested, and acts on adult and larval stages. In the insect CNS it interacts with receptors of gamma-aminobutyric acid (GABA), which regulate chloride channels. It blocks the transfer of chloride ions across cell membranes. This results in excessive nerve stimulation, uncoordinated activity of the nervous system and subsequent death of the insects and mites. Acaricidal effect is also caused by the destructive action on the salivary glands of ticks, which prevents sucking of the animal. Fipronil reproductive toxicity was found in female ticks (irreversible changes in the oocytes).

Pharmacokinetic properties:

After product application the active substance penetrates the skin of the animal, spreads by concentration gradient from the application site to the periphery (lumbar area, groins, etc.), accumulates in the fat component of the skin and hair follicles, from which it is gradually released to the skin and coat. This ensures a long lasting activity. Fipronil is not absorbed into lower layers of skin and subcutaneous tissue after a topical application.

Shelf life:  

Shelf-life of the veterinary medicinal product as packaged for sale: 2 years. Use immediately after opening the bag.

Special precautions for storage:  

This veterinary medicinal product does not require any special temperature storage conditions.
Store in the original container in order to protect from light.Store in a dry place.


1, 3 or 25 single-dose tubes

Not all pack sizes may be marketed.

Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such produc:

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Fipronil may adversely affect aquatic organisms. Do not contaminate ponds, rivers or reservoirs with the product or empty containers.
Medicines should not be disposed of via wastewater or household waste.

Other information:

The veterinary medicinal product is available without prescription.

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