EN - Anglická CZ - Česká SK - Slovenská PL - Polská RO - Rumunská RU - Ruská TR - Turecká UA - Ukrajinská
EN - Anglická
  • CZ - Česká
  • SK - Slovenská
  • PL - Polská
  • RO - Rumunská
  • RU - Ruská
  • TR - Turecká
  • UA - Ukrajinská

BioBos L, suspension for injection

Homepage Products Veterinary products BioBos L, suspension for injection

Inactivated monovalent vaccine against bovine leptospirosis.

type of preparative: Vaccines
target species animals: Cattle

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Pharmaceutical form

Suspension for injection.

Whitish to pinkish milky fluid, separated at longer standing into white sediment and almost clear supernatant.


Leptospira hardjo type hardjo-bovis inact. min. titre 32 determined by ALR*

*The value was determined on the basis of the titres of the reference serum obtained from 5 rabbits vaccinated with a batch compliant with the challenge potency test on the target species (ALR = agglutination-lytic reaction).


For the active immunisation of cattle from 4 weeks of age against leptospirosis (serovar hardjo, type hardjo-bovis) to prevent infection, foetal infection and Leptospira excretion, mainly in the urine.

Onset of immunity: 4 weeks after primary vaccination (i.e. after administration of the first 2 doses).

Duration of immunity: 12 months after primovaccination.

Dosage, application and vaccination scheme

Dose – 2 ml subcutaneously behind the shoulder blade, calves from 4 weeks of age, heifers and cows.

Before use the vaccine must be heated to a temperature between 15 °C and 25 °C and the contents of the vial should be shaken well.

Primary vaccination:

Primovaccination – requires the administration of two vaccine doses in interval of 4–6 weeks, the second dose should be administered not later than 4 weeks prior to mating. The main effect is prevention of Leptospira excretion in the urine.

If the second vaccine dose is administered not later than 2 weeks before mating, there is also a significant prevention of foetal infection.

Calves can be vaccinated from 4 weeks of age, using by primovaccination (i.e. administration of two doses). Heifers are vaccinated once before mating.


To maintain protective immunity, annual revaccination with one dose, administered not later than 2 weeks prior to mating, is necessary.

The product can be used during pregnancy and lactation.


Store and transport refrigerated (2 °C–8 °C).

Protect from frost.

Protect from light.

Store in a dry place.

Withdrawal period

Not applicable.

Shelf life

Shelf life of the veterinary medicinal product as packaged for sale: 2 years.

Shelf life after first opening of package: 10 hours.


10 ml, 50 ml, 100 ml in glass or plastic bottle.

Not all pack sizes may be marketed.