BioBos L(6), suspension for injection
Inactivated polyvalent vaccine against bovine leptospirosis.
|type of preparative:||Vaccines|
|target species animals:||Cattle|
Suspension for injection.
Whitish to pinkish milky fluid, divided at longer standing into white sediment and almost clear supernatant.
Leptospira pomona inact. min. titre 16 determined by ALR*
Leptospira hardjo type hardjo-prajitno inact. min. titre 35 determined by ALR*
Leptospira hardjo type hardjo-bovis inact. min. titre 32 determined by ALR*
Leptospira grippotyphosa inact. min. titre 64 determined by ALR*
Leptospira icterohaemorrhagiae inact. min. titre 81 determined by ALR*
Leptospira canicola inact. min. titre 35 determined by ALR*
*The values were determined on the basis of the titres of the reference serum obtained from 5 rabbits vaccinated with a batch compliant with the challenge potency test on the target species (ALR = agglutination-lytic reaction).
For the active immunisation of cattle from 4 weeks of age against leptospirosis (6 serovares contained in the vaccine) to prevent infection, foetal infection and Leptospira excretion, mainly in the urine.
Onset of immunity: 4 weeks after primary vaccination (i.e. after administration of the first 2 doses).
Duration of immunity: 12 months after basic immunisation.
Dosage, application and vaccination scheme
Dose – 2 ml subcutaneously behind the shoulder blade, calves from 4 weeks of age, heifers and cows.
Before use the vaccine must be heated to a temperature between 15 °C and 25 °C and the contents of the vial should be shaken well.
Primovaccination – requires the administration of two vaccine doses in interval of 4–6 weeks, the second dose should be administered not later than 4 weeks prior to mating. The main effect is prevention of Leptospira excretion in the urine.
If the second vaccine dose is administered not later than 2 weeks before mating, there is also a significant prevention of foetal infection.
Calves can be vaccinated from 4 weeks of age using primovaccination (i.e. administration of two doses). Heifers are vaccinated once before mating.
To maintain protective immunity, annual revaccination with one dose, administered not later than 2 weeks prior to mating, is necessary.
The product can be used during pregnancy and lactation.
Store and transport refrigerated (2 °C–8 °C).
Protect from frost.
Protect from light.
Store in a dry place.
Shelf life of the veterinary medicinal product as packaged for sale: 2 years.
Shelf life after first opening of package: 10 hours.
10 ml, 50 ml, 100 ml in glass or plastic bottle.
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