BioBos Respi 2 intranasal, nasal spray, lyophilisate and solvent for suspension
Intranasal live attenuated vaccine against the most common viral pathogens of Bovine Respiratory Disease Complex.
|type of preparative:||Vaccines|
|target species animals:||Cattle|
Nasal spray, lyophilisate and solvent for suspension.
The lyophilisate has a porous structure, off-white or yellowish colour.
The solvent is clear, colourless solution.
Live attenuated Bovine parainfluenza type 3 virus (PI3V), strain Bio 23/A 105.0–107.5 TCID50
Live attenuated Bovine respiratory syncytial virus (BRSV), strain Bio 24/A 104.0–106.0 TCID50
*TCID50 – Tissue culture infectious dose – 50 %
For active immunization of calves from 10 days of age against BRSV and Bovine PI3V to reduce the amount and duration of excretion of both viruses.
Onset of immunity: 10 days after a single vaccination.
Duration of immunity: 12 weeks after a single vaccination.
Dosage, application and vaccination scheme
Administer one dose (2 ml) of the reconstituted vaccine intranasally (1 ml of the vaccine into each nostril) to calves from 10 days of age using an intranasal applicator.
Aseptically reconstitute the lyophilisate by adding the enough of amount of the solvent into the vial containing the lyophilisate. After dissolution the volume is transferred into vial with solvent. Shake well. Required volume of the reconstituted vaccine is drawn up from the bottle by syringe with a needle, the needle is then replaced by an intranasal applicator and the vaccine is administered. The applicator is used to administer the required volume of the vaccine from the syringe into nostrils of the vaccinated animal in the aerosol form. The applicator used should spray the vaccine in the form of 30 µm to 100 µm droplets.
It is recommended to use a new or cleaned by cellulose applicator for each animal, in order to prevent the transmission of infection.
Store and transport refrigerated (2 °C–8 °C).
Do not freeze.
Protect from direct sunlight.
Store the reconstituted vaccine below 25 °C.
Shelf-life of the veterinary medicinal product (lyophilisate) as packaged for sale: 2 years.
Shelf-life of the solvent as packaged for sale: 4 years.
Shelf life after reconstitution according to directions: 2 hours.
1 x 5 doses, 5 x 5 doses.
Intranasal applicators are not included in package.
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