GAMMAVIT BIO powder for oral suspension
Antibiotic product with vitamins and immunoglobulins for treatment of gastrointestinal diseases of newborn calves
|type of preparative:||Antimicrobial products|
|target species animals:||Cattle|
Composition - 1 g:
- Tetracyclini hydrochloridum 30 mg
- Imunoglobulinum bovinum 20 mg
- Alpha-tocoferoli 1.2 mg
- Retinoli acetas 8 000 IU
- Vitamin D3
- Calcium gluconate
- Disodium hydrogen phosphate
It acts bacteriostatically on G+ and G- bacteria (Clostridium spp., Actinomyces pyogenes, Streptococcus spp., Staphylococcus spp., Actinobacillus pleuropneumoniae, Haemophilus spp., Klebsiella spp., Pasteurella spp., Campylobacter spp., Bacillus spp., Brucella spp., Moraxella spp. and Rickettsia spp.) and certain Protozoa. It does not act on gram-negative non-fermenting rods. Its resistance depends on plasmids. As soon as it diffuses into the cell interior it is actively transported inside it. It inhibits microorganism proteosynthesis by binding to their proteins of 30S-ribosomal subunit. Its strong affinity to polyvalent cations leads to creation of slightly soluble chelates, which intensifies its bacteriostatic action on bacteria, but has a negative effect on its resorption. When administered perorally, it absorbs quickly into the gastrointestinal tract. The therapeutic level in blood is created in 2 to 6 hours. When distributed in an organism, it permeates through the placenta and slightly into the cerebrospinal fluid. It participates in enterohepatic circulation. Its concentrations in bile are many times higher than in blood. High concentrations can also be found in kidneys, liver, spleen and lungs. It becomes deposited in places of active ossification. It is not practically metabolised in organism and is excreted in an active form via glomerular filtration by kidneys and bile in faeces.
Polyvalent, non-specific composition of bovine immunoglobulins acts as a natural immunological protection against the most common gastrointestinal infections in calves. Immunoglobulins bind to specific receptors of bacteria and thus they inhibit them. Bovine immunoglobulins administered perorally act mainly in the intestines. If administered early after birth, a large amount is resorbed into the organism, where they increase the immunoglobulin level in blood and tissues.
Alpha - tocoferoli (Vitamin E)
Acts as an antioxidant that helps stabilize oxidation-sensitive substances such as phospholipids in cellular membrane, vitamin A, carotenoids and other substances in the saccharide metabolism. In a passive way it is absorbed into the intestine from where it is transported in chylomicrons into the liver. Bound to lipoproteins, it is subsequently transported to peripheral tissues, where it supplies the need for cellular membranes and sub cellular structures. It becomes deposited in the liver and adipose tissue. Organisms are not able to simply eliminate possible excess vitamin.
Retinoli acetas (Vitamin A):
It acts positively in development, prevention and regeneration of skin and muscosa, supports creation of antibodies and saccharide, and protein and lipid metabolism regulation. Bound to chylomicrons and lipoproteins, it is transported from the intestine to the liver. From the liver it is transported to tissues in a bond with proteins (protein binding retinol). It exists in 3 oxidation levels, vitamers: retinol, retinaldehyde and retin acid). It becomes deposited in the liver and adipose tissue. Organisms are not able to simply eliminate possible excess vitamin.
Gastrointestinal diseases of newborn calves.
Do not administrate together with other narrow-spectrum antibiotics.
Method of administration and dosage:
One dose is 25 g (1 bag) per calf. Before administration, mix the dose with about 200 ml of tea, colostrum or water heated to 25 - 30 °C. Administrate perorally within 24 hours.
Sporadic allergic reactions may appear in animals.
Store in a dry place, in intact, properly closed original covers at temperatures below 25 oC.
Not designed for food-producing animals.
1 x 25 g
+420 517 318 598