LINEOMAM LC intramammary solution
A product for the intramammary treatment of mastitis in lactating dairy cows with a broad spectrum of activity against the most common causes of infectious bovine mastitis, including Staphylococcus aureus and Escherichia coli.
|type of preparative:||Antimicrobial products|
|target species animals:||Cattle|
1 applicator of 10 ml contains:
Lincomycinum (ut hydrochloridum) 330 mg
Neomycin sulfate 100,000 IU
Intramammary solution. Clear, colourless to yellowish solution.
Dairy cows during lactation.
INDICATIONS FOR USE, SPECIFYING THE TARGET SPECIES
Treatment of mastitis caused by bacteria susceptible to a combination of lincomycin and neomycin in dairy cows during lactation. Bacteria generally susceptible to lincomycin and/or neomycin are bacteria of the genus Staphylococcus spp., including S. aureus, the genus Streptococcus spp. including S. agalactiae, S. dysgalactiae and S. uberis, and coliform bacteria, including E. coli.
SPECIAL PRECAUTIONS FOR USE
Official and local antibiotic policies must be taken into account when using the product.
Use of the product should be based on cultivation and determination of the sensitivity of microorganisms originating from cases of the disease at the farm. If this is not possible, treatment should be based on local (regional, at farm level) epizootiological information on the sensitivity of target bacteria.
Use of the product deviating from the instructions given in this Summary of Product Characteristics (SPC) may increase the prevalence of bacteria resistant to lincomycin or neomycin and reduce the effectiveness of treatment with macrolides and other lincosamides or aminoglycosides due to the potential for cross-resistance.
Do not use disinfectant wipes on teats with open wounds.
USE DURING PREGNANCY AND LACTATION
Can be used during pregnancy and lactation.
INTERACTION WITH OTHER MEDICINAL PRODUCTS AND OTHER FORMS OF INTERACTION
This product should not be used concomitantly with macrolides. The effect of lincomycin and macrolides is antagonistic due to competition for the binding site on the 50S ribosomal subunit, which is the site of the antimicrobial action of both molecules.
Aminoglycosides are synergetic with some beta-lactam antibiotics. Synergism is given by, among other things, the damage of the bacterial wall caused by the action of beta-lactam, which allows the easier penetration of aminoglycoside to the target structure of the bacterial ribosome. This is used, for example, against streptococci and gram-negative bacteria.
AMOUNTS TO BE ADMINISTERED AND ADMINISTRATION ROUTE
For one dose, the contents of 1 applicator is administered to each affected quarter, i.e. 100,000 IU neomycin sulfate and 330 mg lincomycin. A total of 3 doses is applied to each affected quarter. Doses are applied at 12-hour intervals.
Administer the product by intramammary infusion only, taking aseptic precautions. Apply to a clean, washed and thoroughly dried udder, as soon as possible after milking the treated quarter. Prior to application, disinfect the end of the teat using one of the disinfectant wipes provided (use a new wipe for each teat!).
Prior to application, hold the applicator with the cannula pointed upward and remove the cap from the cannula in this position. Immediately after opening, insert the cannula into the teat canal, press the plunger and dispense the entire contents of the applicator into the affected quarter. It is recommended the teat be massaged briefly, away from the tip of the teat towards the milk cistern, following application.
Each applicator is intended for single use only.
Meat: 3 days.
Milk: 84 hours.
Shelf life of the veterinary medicinal product as packaged for sale: 2 years.
Intended for immediate use after first opening.
SPECIAL PRECAUTIONS FOR STORAGE
Do not freeze. Protect from light.
24 x 10 ml, package includes 24 disinfectant wipes moistened with 65% v/v isopropyl alcohol solution
+420 517 318 598