PESTORIN MORMYX lyophilisate and solvent for suspension for injection

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Composition - 1 ml:

Liquid component 

Names  of substances	Quantity	Function
Calicivirus septicemiae haemorrhagiae cuniculi	min. 128 HA, max. 1024 HA	Active substance
Algeldratum	0,2 ml	Adjuvant
Thiomersalum	0.085-0.115 mg	Conservans
Natrii chloridi solutio	ad 1 ml	Diluent

Freeze-dried component  

Names  of substances	Quantity	Function
Poxvirus myxomatosae attenuatum	min. 103,3 TCID50max. 105,8TCID50	Active substance
Nutrimentum pro lyophilizatione	ad 1.0 ml	Protective substance
Nutrimentum MEM	ad 1.0 ml	Culturing medium

Effect method:

Antigens contained in the vaccine administered into the animal body provoke creation of specific antibodies, which then protect the immunized animal against  rabbit haemorhagic disease and  myxomatosis.
Full post-vaccination immunity develops in nine days in case of myxomatosis and in ten days in case of haemorrhagic disease and persists for a period of one year in case of haemorrhagic disease and for a period of six months in case of myxomatosis.

Immunity:

Full immunity  develops againts myxomatosis   9 days and againts pest  2 - 3 weeks after the vaccination, respectively. Animals kept for breeding should be re-vaccinated against myxomatosis in 6-months and and against  pest in 12-months intervals. Considering the disease seasonal incidence, animals should be vaccinated (revaccinated) in time to ensure their full immunity during the whole critical period of infection occurrence.

Indication:

For the preventive immunization of clinically healthy rabbits against rabbit haemorrhagic disease and myxomatosis.

Contraindication:

Ill and cachectic animals. Doe-rabbits should not be vaccinated during the last week of their pregnancy due to the possibility if miscarriage induced by the harsh handling.

Interaction:

Unknown

Preparation for application:

Shake the content of the vial well before use. Dilute the lyophilizate in the liquid vaccine component; the vaccine shall be applied within 2 hours after dilution.

Dosage:

1 ml regardless of animal  size. The following immunization regimen is recommended: Rabbits should be vaccinated at the age of 10 weeks.  
Vaccination can be performed earlier in case of adverse infectious conditions, namely, as follows:
a) Vaccination with the monovalent vaccine against myxomatosis (Myxoren) can be performed at the age of 4 weeks and above followed with the revaccination with the vaccine Pestorin Mormyx that shall be applied not earlier than at the age of 10 weeks. The interval of at least 2 weeks shall be kept between the applications of the vaccines Myxoren and Pestorin Mormyx.
b) Vaccination with the vaccine Pestorin Mormyx can be performed at the age of 6 weeks and above followed by the revaccination performed 4 weeks later.Next revaccinations with the vaccine Pestorin Mormyx is recommended to be performed in 6-month intervals in breeding animals.
Considering the disease seasonal incidence, animals should be vaccinated (re-vaccinated) in time to ensure their full immunity during the whole critical period of infection occurrence. 

Adverse effects:

Unknown

Storage:

Store in a dry and dark place at the temperature of 2 ^oC - 8 ^oC. The vaccine shall not be allowed to freeze!

Withdrawal period:

Rabbits should not be slaughtered for meat for 7 days after the vaccination due to a possible local reaction.

Shelf life:

2 years. Use the vaccine within 2 hours mixing the components!

Package:

5 x 1 doses, 20 ml, 5 x 20 ml.

Not all pack sizes may be marketed. 

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