EN - Anglická CZ - Česká SK - Slovenská PL - Polská RO - Rumunská RU - Ruská TR - Turecká UA - Ukrajinská
EN - Anglická
  • CZ - Česká
  • SK - Slovenská
  • PL - Polská
  • RO - Rumunská
  • RU - Ruská
  • TR - Turecká
  • UA - Ukrajinská

POLYPLEUROSIN APX PLUS IM emulsion for injection for pigs

Homepage Products Veterinary products POLYPLEUROSIN APX PLUS IM emulsion for injection for pigs

Vaccine against porcine pleuropneumonia for intramuscular administration

type of preparative: Vaccines
target species animals: Pig

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Composition - 1 ml:

Actinobacillus pleuropneumoniae serovar 9 - min. 5.6 x 109Actinobacillus pleuropneumoniae serovar 2 - min. 5.6 x 10; Pasteurella multocida serovar A - min. 5.2 x 109 ;
Pasteurella multocida serovar D - min. 2.8 x 109 Bordetella bronchiseptica - min. 4.0 x 109 ;
Apx I toxoid  min. 1.5 µg ; Apx II toxoid min. 1.5 µg ; Apx III toxoid  min. 1.5 µg ; 
Thiomersalum ;  Emulsio olei; Buffered physiological saline.


For immunization of piglets and sows in breeds so far free from or already suffering by pneumonia caused by: Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica.

The vaccine contains A. pleuropneumoniae, P. multocida, B. bronchiseptica bacterial antigens and Actinobacillus pleuropneumoniae Apx I, Apx II and Apx III toxoids. Following parenteral administration, these antigens induce production of specific antibodies that protect the organism against actinobacillus pleuropneumonia and also provide protection against most frequent secondary bacterial pneumonic pathogens that aggravate clinical course of the disease.

Newborn piglets from vaccinated sows receive passive protection against pneumonia by colostral immunity for 14 – 21 days.

Vaccinated piglets become actively immune in 14 days after revaccination, which lasts for 6 months.The vaccine contains inactivated bacteria and toxins that gradually absorb from the site of application.


Existing acute or febrile illness.

Method of administration:

Immunization of piglets: vaccinate piglets with the dose of 1.0 ml i.m.

  • Primovaccination: from 6 weeks of age
  • Revaccination: 2-3 weeks later

Immunization of sows: vaccinate sows with the dose of 1.0 ml i.m.

  • Initial vaccination: 6 - 4 weeks before delivery.
  • Vaccination in 2-3 weeks, but not later than 2 weeks before delivery.
  • Further revaccinations: regularly 3 to 2 weeks before every next delivery.

If the period between two deliveries exceeds 8 months, another initial vaccination and revaccination will be necessary.
Route of administration: intramuscularly, preferably into the paraauricular area.

Dosage form:

Injection solution

Adverse effects:

Slight apathy and somnolence may occur following application, which will die away in several hours. Small isolated fibrous nidae at the site of injection may occur in the muscle. When examining the meat of slaughtered pigs, the altered tissue must be removed.

Use during pregnancy, lactation

Vaccination and revaccination of pregnant sows should end no later than 14 days before the anticipated delivery.


Heat the vial content to a room temperature and shake before use.


Store in a dry and dark place at a temperature of 2 to 8 °C. The vaccine must not freeze!

The preparation must not be used after the lapse of the applicability period, indicated on the package.

Protection period:

Without withdrawal periods.

Shelf life:

18 months.
Shelf-life after first opening – 10 hours.


The vaccine is shipped in glass or plastic vials hermetically closed by rubber puncturable stoppers with aluminium caps. Vials with the vaccine are placed in paper cartons.

100 ml in glass vials and 250 ml in plastic bottles

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+420 517 318 598