TRICHOBEN AV lyophilisate and solvent for suspension for injection for cattle
Vaccine for active immunisation of cattle to reduce clinical signs of dermatophytosis caused by Trichophyton verrucosum for prophylactic vaccination and for therapeutic use
|type of preparative:||Vaccines|
|target species animals:||Cattle|
Composition - 1 ml:
Trichophyton verrucosum avirulentum strain TV-M-310 min. 3.125 x 106 CFU, max. 18.75 x 106 CFU
Excipients: 0.8% sodium chloride solution
Diluent A 1 ml
For active immunisation of cattle to reduce clinical signs of dermatophytosis caused by Trichophyton verrucosum for prophylactic vaccination and for therapeutic use.
Immunity is created within 1 month after revaccination and it persists at least one year.
During vaccination and revaccination, it is necessary to avoid administration of the preparation to the same site (or close to it). Due to that, it is strictly contraindicated to administer the preparation during vaccination and revaccination to the same half of the body.
Performance of other immunoprophylactic procedures in the period of 10 days prior to the first vaccination until 20 days after the second vaccination or administration of oral preparations with antimycotic effects to calves and placing the vaccinated animals among cattle affected with trichophytosis are contraindicated. If it is necessary to treat calves with antibiotic preparations during vaccination against trichophytosis, it is possible to use penicillin, streptomycin, tylosine, tetracycline or sulphonamide without any risk of significant impairment of immunity against trichophytosis.
A general anaphylactoid reaction can rarely occur, usually within two hours after the administration of the vaccine. Use anti-histamine drugs (adrenalin, calcium) immediately in case of an anaphylactoid reaction.
Cattle from the age of 3 weeks.
Dosage for each species, route and method of administration:
Prophylactic and therapeutic:
- calves from the age of one day till the age of three months 2 x 2 ml
- cattle over the age of three months 2 x 4 ml
Interval between vaccination and revaccination is 5 – 14 days.
Method of administration:
Intramuscular to the lumbar or gluteal region. Vaccination and revaccination must be performed always to the opposite half of the body. We recommended performance of vaccination into the left half of the body; revaccination should be made into the right half of the body.
Advice on correct administration:
Lyophilisate is diluted with Diluent A before use. Use rubber gloves during vaccination.
Meat - 14 days.
Special storage precautions:
Keep and transfer refrigerated (2 °C – 8 °C). Do not freeze. Protect from light.
Keep out of the reach of children. The vaccine must be used within two hours after reconstitution.
Do not use the product after shelf life indicated on the cover.
Latent disease could be triggered during vaccination of animals in the incubation period of the disease. The clinical condition is temporarily worse, but trichophytic changes on skin in the animal gradually subside without any therapeutic intervention.
All animals in the stables must be vaccinated. Vaccination is also necessary after storing all newly stopped 1-2 month calves and animals transferred, since Trichophyton verrucosum is very resistant and survives in the environment for 6-8 years.
Special precautions for the disposal of unused product or waste materials:
Used vials and devices need to be inactivated; they cannot be left in the stable. It is appropriate to use 2 % Ajatin solution, 1 % peracetic acid solution (for a period of 4 hours) for inactivation or it is possible to perform heat inactivation (100 °C, 2 hours).
Interaction with other medicinal products and other forms of interaction:
Oral treatment with antimycotic agents is not recommended together with vaccination. There is no information available concerning compatibility of this vaccine with others. Therefore safety and efficiency of this preparation, if used with other, were not demonstrated.
For animal treatment only – to be supplied only on veterinary prescription.
5 x 10 ml, 1 x 40 ml, 1 x 80 ml
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